Protease enzyme - List of Manufacturers, Suppliers, Companies and Products

Cysteine protease 'FabRICATOR Z (IdeZ)'

Cutting just below the hinge region of mouse IgG! There is no risk of over-digestion due to the high specificity of the enzyme!

"FabRICATOR Z (IdeZ)" is a cysteine protease that cleaves specific sites downstream of the hinge region of mouse IgG2a and IgG3, generating a homogeneous pool of F(ab')2 and Fc fragments after 2 hours of incubation. Some mouse IgG2a that cannot be digested by FabRICATOR can be easily digested with this product, although a longer incubation time may be required. Additionally, due to the high specificity of the enzyme, there is no risk of over-digestion. 【Features】 ■ Cleaves specific sites downstream of the hinge region of mouse IgG2a and IgG3 ■ Generates a homogeneous pool of F(ab')2 and Fc fragments after 2 hours of incubation ■ Some mouse IgG2a can be easily digested ■ No risk of over-digestion due to the high specificity of the enzyme *For more details, please refer to the PDF document or feel free to contact us.

Company：重松貿易大阪本社
Price：Other

Other restriction enzymes
Research Antibodies
Other protein analysis

Added to bookmarks

Bookmarks list

Bookmark has been removed

Bookmarks list

You can't add any more bookmarks

By registering as a member, you can increase the number of bookmarks you can save and organize them with labels.

Free membership registration

Cysteine protease "GingisKHAN (Kgp)"

Cleavage of the upper region of the human IgG1 hinge! Produces intact and homogeneous Fab and Fc fragments.

"GingisKHAN (Kgp)" is a cysteine protease that cleaves human IgG1 at a specific site upstream of the hinge region, producing intact and homogeneous Fab and Fc fragments. This enzyme is used for the characterization of antibody-based biological therapies using LC-MS, Fc glycan analysis, studies on the effects of bispecific antibodies, affinity and binding strength, as well as the identification of post-translational modifications. [Features] - Cleaves human IgG1 at a specific site upstream of the hinge region - Produces intact and homogeneous Fab and Fc fragments - Used for the characterization of antibody-based biological therapies using LC-MS, Fc glycan analysis, studies on the effects of bispecific antibodies, affinity and binding strength, and the identification of post-translational modifications *For more details, please refer to the PDF document or feel free to contact us.

Company：重松貿易大阪本社
Price：Other

Other restriction enzymes
Research Antibodies
Other protein analysis

Added to bookmarks

Bookmarks list

Bookmark has been removed

Bookmarks list

You can't add any more bookmarks

By registering as a member, you can increase the number of bookmarks you can save and organize them with labels.

Free membership registration

Protease 'GingisREX (RgpB)'

Specifically cleaves proteins at arginine! It also cleaves when the adjacent amino acid is proline!

"GingisREX (RgpB)" is an arginine-specific protease that cleaves proteins at the C-terminal of arginine residues. It is capable of cleaving arginine-proline sequences, which are difficult to cleave with other enzymes. This enzyme is useful for peptide mapping, de novo peptide sequencing, and the analysis of post-translational modifications. 【Features】 - Cleavage is possible even when the adjacent amino acid is proline. - Compared to cleavage by trypsin, longer peptides are generated, allowing for separation and identification using high-resolution MS. - Increases options for sample preparation for bottom-up approaches, improving degradation profiles and sequence coverage. - Shows activity over a wide pH range of 5.0-9.0, requires cysteine, but is inhibited by guanidine hydrochloride. *For more details, please refer to the PDF document or feel free to contact us.*

Company：重松貿易大阪本社
Price：Other

Other restriction enzymes
Research Antibodies
Other protein analysis

Added to bookmarks

Bookmarks list

Bookmark has been removed

Bookmarks list

You can't add any more bookmarks

By registering as a member, you can increase the number of bookmarks you can save and organize them with labels.

Free membership registration

Protease "OpeRATOR"

Specifically cleave proteins with O-glycans! Intermediate-level approaches using MS analysis are also possible!

"OpeRATOR" is a specific protease that cleaves the N-terminal residues of Ser and Thr in glycan residues of proteins with mucin-type O-linked glycans. O-linked glycopeptides are generated, allowing for O-linked glycan profiling, peptide mapping, determination of site occupancy, and intermediate-level approaches through MS analysis. 【Features】 ■ Specifically cleaves proteins with O-linked glycans ■ Generates O-linked glycopeptides ■ Enables O-linked glycan profiling, peptide mapping, determination of site occupancy, and intermediate-level approaches through MS analysis ■ Does not digest glycoproteins at N-linked glycan sites *For more details, please refer to the PDF document or feel free to contact us.